Upstate South Carolina Vacations from $318
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Your Upstate South Carolina Vacation
When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.
The Latest Upstate South Carolina vacation packages
Price found within the past 48 hours. Click for updated prices.
Fairway Forest
Save 100% on your flight
Price was $567, price is now $318 per person
$318
per person
Dec 25 - Dec 30
found 1 day ago
Roundtrip flight included
Miami (MIA) to Asheville (AVL)
17.6/10 Exceptional! (293 reviews)
We've stayed here a number of times. Always friendly and a pleasure to deal with. The renivated rooms were a nice surprise too!
Reviewed on Nov 13, 2025
Hotel Hartness
Save 100% on your flight
Price was $765, price is now $452 per person
$452
per person
Jan 30 - Feb 2
found 2 hours ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Greenville (GSP)
19.6/10 Exceptional! (613 reviews)
Excellent staff and facilities. Very clean, comfortable and welcoming atmosphere and very enjoyable stay
Reviewed on Nov 13, 2025
Foxhunt at Sapphire Valley
Save 100% on your flight
Price was $543, price is now $364 per person
$364
per person
Dec 25 - Dec 30
found 1 day ago
Roundtrip flight included
Miami (MIA) to Asheville (AVL)
18/10 Exceptional! (437 reviews)
Room was clean, the area around the property is magical. Really recommend staying here!
Reviewed on Nov 10, 2025
Homewood Suites by Hilton Greenville Downtown
Greenville Downtown
Price was $465, price is now $341 per person
$341
per person
Jan 30 - Feb 2
found 2 hours ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Greenville (GSP)
19.2/10 Exceptional! (1,003 reviews)
Great room, great staff, excellent breakfast, super clean. perfect location.
Reviewed on Nov 17, 2025
Best Western Plus Clemson Hotel & Conference Center
Price was $427, price is now $324 per person
$324
per person
Jan 30 - Feb 2
found 2 hours ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Greenville (GSP)
16.4/10 Exceptional! (1,007 reviews)
Look like someone got sick in the sink. What not cleaned up
Reviewed on Nov 11, 2025
Don't see what you're looking for?
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View all tripsWhere to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown
3 out of top 10 points of interest in this area
5/5(654 area reviews)
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Discover the most popular places to visit in Upstate South Carolina
Clemson University
5/5(410 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
Memorial Stadium
5/5(129 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.
Falls Park on the Reedy
4.5/5(583 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.
What to do in Upstate South Carolina
Small-Group Walking Tour in Greenville with Breakfast
$95
per adult
100% of travellers recommend
Epic City Scavenger Hunt in Garden Grove by Operation City Quest
$10
per adult
Upstate South Carolina Hotel Deals
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $101 total per night from Nov 23 to Nov 24
$101 total
Nov 23 - Nov 24
Total with taxes and fees
8.2/10 Very Good! (1,006 reviews)
Everything was great
Reviewed on Nov 14, 2025
Hyatt Regency Greenville
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $180 total per night from Nov 23 to Nov 24
$180 total
Nov 23 - Nov 24
Total with taxes and fees
8.6/10 Excellent! (1,000 reviews)
Convenient to Main Street area.
Reviewed on Nov 8, 2025
La Quinta Inn & Suites by Wyndham Greenville Haywood
65 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $76 total per night from Nov 23 to Nov 24
$76 total
Nov 23 - Nov 24
Total with taxes and fees
7.2/10 Good! (1,113 reviews)
Room was clean. Breakfast was good. Staff was very nice and helpful! Exhaust fan in the bathroom would have been appreciated.
Reviewed on Nov 14, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Upstate South Carolina Vacation Packages
Upstate South Carolina Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charlotte-Douglas Intl. Airport (CLT) |
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- Golden Lanes and Golden Skate
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- Gravitopia Trampoline Arena
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- Old Towne Shopping Center
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- Lakeside Park
- Lewis Plaza Shopping Center
- Runway Park at GMU
- Prisma Health Greenville Memorial Hospital
- Roper Mountain Science Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
